Three-dimensional microscopy reconstruction of a melanoma cell
Melanoma cell, NCI Visuals OnlineDonald Bliss (NLM) / Sriram Subramaniam

Volunteer compute infrastructure for cancer research

Put unused powerbehind the cure.

Apoptosis is building nonprofit infrastructure that can connect idle CPU and GPU capacity with verified cancer research teams— safely, transparently, and at meaningful scale.

Technical prototype builtFounding partners soughtSecurity review next
Dispatch model / prototypePilot phase
NODE / OPT-INVolunteer GPUContributor controlled
APSecure dispatch
QUEUE / REVIEWEDResearch jobInstitution verified
ContainerizedResource limitedResult checked
04
Prototype surfaces

Donor app, agent, dispatch API, researcher portal

04
Workload families

Molecular, genomic, docking, and model validation

02×
Validation design

Independent execution before results are accepted

90
Day pilot target

A controlled institutional proof before public scale

Architecture and pilot targets—not live research impact claims.

Why apoptosis?

Apoptosis is the process that tells damaged cells to self-destruct. Cancer learns to ignore that signal.

This project exists to put more computing power behind the researchers working to understand and restore it.Built in memory of Kait Shannon.

The opportunity

Compute access should not decide which questions get asked.

Modern cancer research depends on large, parallel workloads. Institutional infrastructure is essential, but suitable exploratory work can still compete for finite capacity. Meanwhile, powerful personal hardware spends long stretches idle. Apoptosis is engineering a trusted bridge between the two.

01 / Research

More questions than capacity

Compute-intensive experiments can queue behind other institutional work, slowing iteration for smaller and early-stage teams.

02 / Hardware

Capable machines waiting to help

Modern consumer CPUs and GPUs can contribute meaningful parallel work when the owner is not using them.

03 / Connection

Infrastructure with one purpose

A reviewed dispatch layer can turn voluntary capacity into complementary research infrastructure.

Prototype code today

The system already has a spine.

The current prototype models the full path from contributor control to research job submission. The next phase is not adding a prettier dashboard—it is validating the architecture under independent review and a real institutional workload.

01
Donor experienceReact donor app

Control stays with the contributor.

Node registration, live status, resource throttling, contribution history, and a visible pause control.

02
Local agentNode agent + Docker

Jobs run inside defined limits.

Heartbeat reporting, task receipt, isolated container execution, and fallback polling for resilient operation.

03
Dispatch coreAPI + PostgreSQL + Redis

Work is split, assigned, and checked.

Authenticated APIs, job queues, real-time events, task assignment, timeout handling, and redundant result comparison.

04
Researcher portalReact research portal

Access begins with verification.

Institutional applications, reviewed access, job submission, progress monitoring, and result retrieval.

One network, two communities

Contribution without complexity.

The contributor keeps control. The research institution keeps oversight. Apoptosis handles the secure coordination between them.

01

A contributor opts in

The donor chooses when the agent can run, how much capacity it may use, and when it should pause.

02

A verified job is prepared

An approved institution submits a divisible, container-compatible workload for technical and security review.

03

The network does the work

Jobs are split, assigned, monitored, and checked before validated results are returned to the research team.

For future compute donors

Your hardware. Your limits. Visible impact.

  • Choose resource limits and pause at any time
  • See the approved project your machine supports
  • Public release follows independent security review
Join the launch network

For research teams

Bring a workload that can travel.

  • Divisible, container-compatible compute jobs
  • Institutional verification and pilot scoping
  • Reference outputs for result comparison
Scope a research pilot

Trust before scale

Designed so confidence can be earned.

Volunteer hardware should never require blind trust, and researchers should never accept unverifiable output. The platform is being built around controls that can be inspected, tested, and improved before public launch.

Readiness gateIndependent security review, adversarial testing, reference-run validation, and pilot remediation are required before the public donor network opens.
01

Verified research access

Institutional identity checks and manual review are part of the access model before a research workload reaches the network.

02

Isolated execution

The architecture uses containerized jobs, resource limits, non-root execution, and network-isolated workloads on volunteer hardware.

03

Results checked twice

The pilot design assigns task chunks to independent nodes and compares outputs before results are accepted.

04

Inspectable donor software

The donor-side agent is intended for open release so contributors and reviewers can inspect what runs on a machine.

Security teams can request the prototype architecture and help define the independent review scope.

Review the security model

Pilot workload families

Built for work that divides cleanly.

Final pilot eligibility depends on data sensitivity, container design, expected runtime, hardware variance, and independent technical review.

01

Molecular simulation

Protein-folding and molecular-dynamics workflows such as OpenMM and GROMACS.

02

Genomic alignment

Parallel sequence-comparison workflows using tools such as BLAST and BWA.

03

Drug docking

High-volume ligand-docking batches for early-stage compound screening.

04

Model validation

Divisible machine-learning training and validation jobs on approved datasets.

The first proof

A controlled pilot with measurable exit criteria.

The target is a 90-day institutional workload that can be compared against a trusted reference environment. Success is evidence—not vanity metrics.

Workload fit
  • Divisible and container-compatible
  • No identifiable patient data on donor nodes
  • Reference outputs available for comparison
  • Tolerant of variable contributor hardware
Measures
  • Completed and validated compute hours
  • Result accuracy against the reference run
  • Completion rate and recovery from node loss
  • Contributor retention at 30, 60, and 90 days
Propose a workload

From prototype to proof

A disciplined path to the first research result.

  1. Now
    Technical prototype

    Donor, researcher, dispatch, and job-management surfaces.

  2. Next
    Security validation

    External review, adversarial testing, and remediation.

  3. Pilot
    Institutional workload

    Measured results against an approved reference environment.

  4. Scale
    Public donor network

    Open participation backed by published impact reporting.

The founding network

Four ways to move the project forward now.

Apoptosis is deliberately opening with partners, reviewers, and a controlled pilot—not a premature public download.

01

Research institutions

Bring the first reference workload.

A suitable pilot is divisible, container-compatible, benchmarkable against trusted infrastructure, and free of identifiable patient data on donor machines.

Scope a pilot
02

Security reviewers

Challenge the architecture before donors trust it.

The next readiness gate is an independent review of isolation, authentication, task integrity, and the donor threat model.

Review the model
03

Hardware and funding partners

Fund proof, not promises.

Support the security review, controlled pilot infrastructure, contributor hardware, or a mission-led launch to the gaming community.

Discuss sponsorship
04

Future compute donors

Be first when the public agent is ready.

Join the launch network now. Installation will open only after independent security review and pilot remediation.

Join the launch list

Clear answers

What is ready—and what comes next.

Can I install the donor agent today?

Not publicly yet. A technical prototype exists, but installation opens only after independent security review, remediation, and a controlled institutional pilot.

What makes a research workload a good fit?

Strong candidates are divisible, container-compatible, tolerant of variable hardware, benchmarkable against a trusted reference, and do not require identifiable patient data on volunteer machines.

Is this replacing institutional HPC?

No. The goal is to complement trusted research infrastructure with elastic capacity for suitable workloads—not replace secure systems, ethics review, or institutional oversight.

Is Apoptosis already a registered charity?

The project documentation includes Canadian nonprofit, charitable registration, and US 501(c)(3) preparation materials. Those are filing plans, not a claim that current contributions are tax-deductible.

How can an organization help now?

Research teams can propose a pilot workload. Security experts can support architecture review. Hardware and funding partners can help bring the first independently validated pilot online.

Founding partners wanted

The hardware exists.Let's aim it at something that matters.

Bring a pilot workload, challenge the security model, or help fund the first trusted proof of volunteer compute for cancer research.

get-apoptosis.online